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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28352 | PDE9-IN-(S)-C33 | (S)-C33 | PDE |
PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research. | |||
T12389 | PDE-9 inhibitor | Others | |
PDE-9 inhibitor is used for treatment neurodegenerative diseases. | |||
T12395 | PDE9-IN-1 | PDE | |
PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM). | |||
T61833 | Tovinontrine | IMR-687 | PDE |
Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM fo... | |||
T81534 | PDE11A4-IN-1 | ||
PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2, PDE7, PDE8, and PDE9 [1]. | |||
T38899 | Irsenontrine | E2027,Irsenontrine | |
Irsenontrine (E2027) is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9), primarily used for researching neurological diseases. | |||
T24163 | IMR687 | IMR-687,IMR 687 | |
IMR687 is a PDE9 inhibitor that slows or stops the hydrolysis of cGMP. IMR687 can be regarded as a highly promising drug against Alzheimer's for improving memory. | |||
T39108 | Irsenontrine maleate | E2027 maleate | |
Irsenontrine (E2027) maleate is a selective and orally active inhibitor of phosphodiesterase 9 (PDE9). It can be utilized in the study of neurological diseases. | |||
T61770 | (R)-Irsenontrine | ||
(R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine, serves as a potent inhibitor of phosphodiesterase 9 (PDE9) with an inhibition concentration (IC50) of 0.041 μM, primarily utilized in the research of neurol... |